CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 412
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 16

Member Superfamilies of This Class

Superfamily NameFamilies
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 5
Caspase-1 and Disintegrin Binder Superfamily 4
Cathepsin S and Cathepsin L1 Binder Superfamily 2 5
Disintegrin and A disintegrin Binder Superfamily 3
Furin and Genome polyprotein Binder Superfamily 2
Galanin receptor type 2 and Sphingosine 1-phosphate receptor 3... 3
Glutamate receptor ionotropic, NMDA 2B and Corticosteroid 11-b... 3
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Sup... 6
Histamine H3 receptor and Dipeptidyl peptidase 4 Binder Superf... 5
HIV-1 protease Inhibitor Lopinavir Superfamily 4
MBX-102 Superfamily 3
Neprilysin and Integrin beta-1 Binder Superfamily 7
Plitidepsin Superfamily 11
Prelamin-A/C and Histone deacetylase 9 Binder Superfamily 5
Putative 1 3-disubstituted 2-azetidinone Antibitotics and Oxac... 3
Scytalone dehydratase and Cannabinoid receptor 1 Binder Superf... 5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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