CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 418
Functional Category Approved Drug with Natural Product
No. of Members 12

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2
Beta-lactamase and Retinal dehydrogenase 1 Binder Superfamily 9 2
Cruzipain and Prelamin-A/C Binder Superfamily 12 2
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 3
Kappa-type opioid receptor and Delta-type opioid receptor Bind... 4
Menin and Cytochrome P450 3A4 Binder Superfamily 2 2
Mitogen-activated protein kinase 14 and Serine/threonine-prote... 8
NADPH oxidase 4 and DNA polymerase beta Binder Superfamily 1
Niemann-Pick C1-like protein 1 Inhibitor Ezetimibe Superfamily 3
Oestrogen receptor Ligand Mprp Superfamily 3
Putative Bicyclic-aromatic Compounds In Patent EP0832081,US614... 5
Survival motor neuron protein and Menin inhibitor CHEMBL141298... 1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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