CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 426
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 16

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 9
ahydropyrano[3,2-c]chromene NP ZINC04023039 and 4-(9H-xanthen-... 4
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 8
Androgen receptor and Cannabinoid receptor 2 Binder Superfamily 5
Carbonic anhydrase 2 Inhibitor Sulfamic Acid Chroman-2-ylmethy... 6
Cyclooxygenase inhibitor salicylate derivative Aspirin Superfa... 4
D-amino-acid oxidase inhibitor 5-hydroxy-2-(naphthalen-1-yloxy... 5
DNA-(apurinic or apyrimidinic site) lyase and Thyroid hormone ... 14
Gamma-aminobutyric acid A receptor Ligand Fospropofol Superfamily 5
Histone deacetylase 2 and Histone deacetylase 1 Binder Superfa... 4
NP Agn-pc-05grlk Family 1
Prelamin-A/C and Cytochrome P450 2C9 Binder Superfamily 2 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 8
Putative Organic Electroluminescent Polymer For Light Emitting... 5
Putative Patent EP0702668,EP0722430,EP0975586,US5872137,US6071... 4
Silane Derivatives For Liquid Crystals In Patent US5912377,US5... 11

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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