CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 44
Functional Category Approved Drug with Natural Product
No. of Members 12

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 Binder ... 12
Calpain-2 catalytic subunit and Lysosomal alpha-glucosidase Bi... 2
Carbonic anhydrase 2 Binder Superfamily 11 3
Cruzipain and Microtubule-associated protein tau inhibitor CHE... 1
Disintegrin and Stromelysin-1 Binder Superfamily 3
DNA topoisomerase 2-beta inhibitor acridine derivative Amsacri... 3
Glucose-dependent insulinotropic receptor ligand N-[3-(3-cyano... 3
NF-kappa-B and Retinal dehydrogenase 1 Binder Superfamily 3
Nonstructural protein 1 and Menin Binder Superfamily 3 1
Progesterone receptor and Androgen receptor Binder Superfamily 3 5
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 5
Putative Patent EP0734378,US5444056,WO9516674 Superfamily 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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