CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 51
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 14

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Superfamily 5
Alpha-galactosidase A and Nuclear receptor ROR-gamma ligand CH... 3
Angiotensin-converting enzyme inhibitor (2S,4S)-1-[(2S)-2-meth... 2
Beta-lactamase and Cathepsin B Binder Superfamily 2 2
Cytochrome P450 2C9 and Cytochrome P450 2C19 Binder Superfamily 3 3
Gadoxetate Superfamily 5
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 5
Muscarinic acetylcholine receptor M1 Ligand Fesoterodine Fumar... 5
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 3
Nuclear receptor ROR-gamma and Ras-related protein Rab-9A Bind... 6
Putative Patent EP0230020,US4668690,US5100889 Superfamily 2
Sodium- and Beta-lactamase Binder Superfamily 3 5
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 5
Vernakalant Superfamily 6

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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