CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 608
Functional Category Approved Drug with Human Metabolite
No. of Members 9

Member Superfamilies of This Class

Superfamily NameFamilies
20S proteasome Inhibitor Carfilzomib Superfamily 4
Beta-secretase 1 and Caspase-4 Binder Superfamily 6
Chymase and Nociceptin receptor Binder Superfamily 5
Disintegrin and metalloproteinase domain-containing protein 17... 3
Integrin beta-5 and Integrin alpha-V Binder Superfamily 2
Neuropeptide Y receptor type 1 Ligand GI-264879A Superfamily 4
Prostate-specific antigen Binder Superfamily 3
Prothrombin Inhibitor Ximelagatran Superfamily 6
Renin and Legumain-like protease Binder Superfamily 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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