CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 656
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 23

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 18
Beta-lactamase and Nuclear receptor ROR-gamma Binder Superfami... 3
Bifunctional epoxide hydrolase 2 and Aldose reductase Binder S... 4
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 17
Cannabinoid receptor 2 and Aromatase Binder Superfamily 5
Collagenase 3 and B2 bradykinin receptor Binder Superfamily 6
Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2... 6
Hepatocyte growth factor receptor and Vascular endothelial gro... 6
Huntingtin and Beta-lactamase Binder Superfamily 26 6
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 8
Microtubule-associated protein tau and Relaxin receptor 1 liga... 3
Mitogen-activated protein kinase 1 and Prelamin-A/C Binder Sup... 4
Mitogen-activated protein kinase 14 Binder Superfamily 10 3
Multidrug resistance-associated protein 1 Inhibitor Biricodar ... 3
Neprilysin and Leukotriene A-4 hydrolase Binder Superfamily 5
Peptidyl-prolyl cis-trans isomerase FKBP1A and Collagenase 3 B... 11
Poly [ADP-ribose] polymerase 1 and Metabotropic glutamate rece... 3
Prelamin-A/C and Beta-lactamase Binder Superfamily 176 5
Prostaglandin E2 receptor EP4 subtype and Integrase Binder Sup... 7
Putative Patent EP0077090,US4419352,US4471119,US4614802 Superf... 2
Substance-K receptor and Neuromedin-K receptor Binder Superfamily 6
Vascular endothelial growth factor receptor 2 Binder Superfamily 8
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 4

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



81893 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543