CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 667
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 12

Member Superfamilies of This Class

Superfamily NameFamilies
Benzotriazole And Pyrrolidine Derivatives In Patent US4236013,... 4
Cruzipain and Cationic trypsin Binder Superfamily 7
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 4
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 9
Histamine H1 receptor Ligand Mizolastine Superfamily 8
Huntingtin and Pyruvate kinase PKM Binder Superfamily 4
Melanin-concentrating hormone receptor 1 and Mu-type opioid re... 2
Menin and Beta-lactamase Binder Superfamily 42 1
Progesterone receptor and D(2) dopamine receptor Binder Superf... 14
Putative Benzimidazole Insecticides In Patent US4122184 Superf... 3
Reverse transcriptase/RNaseH and Retinal dehydrogenase 1 Binde... 3
Tryptase and Adenosine receptor A1 Binder Superfamily 9

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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