CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 716
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 12

Member Superfamilies of This Class

Superfamily NameFamilies
3-hydroxy-3-methylglutaryl-coenzyme A reductase Binder Superfa... 2
Beta-lactamase and Peptidyl-prolyl cis-trans isomerase NIMA-in... 4
BIBT986 Superfamily 9
CC-486 Superfamily 8
Coagulation factor X and Coagulation factor IX Binder Superfam... 4
Disintegrin and metalloproteinase domain-containing protein 17... 4
Nuclear receptor ROR-gamma and Ras-related protein Rab-9A Bind... 1
Pol polyprotein and Integrin beta-3 Binder Superfamily 8
Prothrombin Inhibitor Dabigatran Superfamily 4
Putative Bipolar Electrophotographic Elements and Substituted ... 4
Type-1B angiotensin II receptor and NS3 Binder Superfamily 7
Tyrosine-protein kinase ITK/TSK Binder Superfamily 6

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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