CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 1002
Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
No. of Members 15

Member Superfamilies of This Class

Superfamily NameFamilies
Arachidonate 5-lipoxygenase-activating protein Inhibitor AM103... 4
Beta-lactamase and Muscleblind-like protein 1 Binder Superfami... 1
Beta-lactamase and Neuropeptide S receptor Binder Superfamily 11 3
Bile acid receptor ligand pyridin-4-yl (1R,3aS,5aR,5bR,7aR,9S,... 3
DNA polymerase beta and Niemann-Pick C1 protein Binder Superfa... 2
Lethal factor and Cholinesterase Binder Superfamily 5
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Superfamily 5
Nicotinic acetylcholine receptor Ligand AZD0328 Superfamily 13
Prelamin-A/C and Beta-lactamase Binder Superfamily 105 8
Prelamin-A/C and Lysosomal alpha-glucosidase Binder Superfamily 1
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Superfa... 6
Renin and Prostaglandin E2 receptor EP3 subtype Binder Superfa... 3
Reverse transcriptase and Hemoglobin subunit alpha Binder Supe... 6
Sodium-dependent serotonin transporter and Transporter Binder ... 7
Thyrotropin receptor and Dipeptidyl peptidase 4 Binder Superfa... 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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