CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 840
Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
No. of Members 15

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 2A and Mitogen-activated protein ... 7
Acetylcholinesterase and Bifunctional epoxide hydrolase 2 Bind... 4
Beta-secretase 1 and Beta-secretase 2 Binder Superfamily 5 4
C-C chemokine receptor type 3 Binder Superfamily 2 4
Cannabinoid receptor 1 Binder Superfamily 4 2
Cathepsin K and Histamine H3 receptor Binder Superfamily 6
D(3) dopamine receptor Ligand SB-277011 Superfamily 6
Glutamate receptor 1 Ligand Piriqualone Superfamily 7
KiSS-1 receptor and Neuromedin-B receptor Binder Superfamily 5
Macrophage colony-stimulating factor 1 and Vascular endothelia... 3
Melanin-concentrating hormone receptor 1 and Serine/threonine-... 7
Protein kinase C beta type and Glycogen synthase kinase-3 beta... 7
Serine/threonine-protein kinase mTOR and DNA-dependent protein... 4
Substance-P receptor Ligand TAK-637 Superfamily 8
Vasopressin V2 receptor Ligand YM-35278 Superfamily 14

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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