CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 850
Functional Category Clinical Trial Drug with Natural Product
No. of Members 19

Member Superfamilies of This Class

Superfamily NameFamilies
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 4
Aurora kinase A and Ephrin type-A receptor 3 Binder Superfamily 4
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 2
Dihydrofolate reductase and Cholecystokinin receptor type A Bi... 7
Huntingtin and Arachidonate 15-lipoxygenase Binder Superfamily 3
Huntingtin and D(2) dopamine receptor Binder Superfamily 2 2
Integrin beta-1 and Integrin alpha-4 Binder Superfamily 7 4
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 10
Nitric oxide synthase, inducible and Acyl-CoA desaturase 1 Bin... 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8
Pol polyprotein and Renin Binder Superfamily 3
Prelamin-A/C and Cellular tumor antigen p53 Binder Superfamily 17 4
Prothrombin and Cytochrome P450 3A4 Binder Superfamily 5
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Su... 11
Renin and Beta-secretase 1 Binder Superfamily 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Superfa... 5
Tubulin alpha-1A chain inhibitor AC1OCF0R Superfamily 4
Tyrosine-protein kinase SYK Binder Superfamily 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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