CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Class Information

Class Name Class 1208
Functional Category Clinical Trial Drug
No. of Members 15

Member Superfamilies of This Class

Superfamily NameFamilies
5-hydroxytryptamine receptor 1A Ligand CP-293019 Superfamily 6
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 10
Endothelin-1 receptor and Endothelin B receptor Binder Superfa... 3
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 6
Glucose-dependent insulinotropic receptor and Cathepsin K Bind... 4
Huntingtin and Ras-related protein Rab-9A Binder Superfamily 3 4
Macitentan Superfamily 4
Menin and Huntingtin Binder Superfamily 28 8
Mitogen-activated protein kinase 14 Inhibitor Pamapimod Superf... 6
P2X purinoceptor 2 and P2X purinoceptor 3 Binder Superfamily 3
P2X purinoceptor 3 and P2X purinoceptor 2 inhibitor 5-(4-bromo... 2
Prelamin-A/C and Dihydrofolate reductase Binder Superfamily 2
Prelamin-A/C and Nuclear receptor ROR-gamma Binder Superfamily 27 2
Proto-oncogene tyrosine-protein kinase receptor Ret and Bifunc... 6
Putative Patent US5677323 Family 1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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