CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSAD350
Superfamily Name HMG-CoA reductase inhibitor Statins Rosuvastatin, Endothelin receptor ligand Ambrisentan superfamil
Functional Category Approved Drug with Natural Product
No. of Members 4
Class Class 328

Member Families of This Superfamily

Family NameSeedsMembers
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor Stat... 2 4
Endothelin-1 receptor Ligand Ambrisentan Family 12 40
propan-2-yl 2-[4-[[N'-(4,6-dimethylpyrimidin-2-yl)carbamimidoy... 1 0
Putative Phosphorus-containing Hmg-coa Reductase Inhibitors In... 1 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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