CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSAD48
Superfamily Name Monoamine reuptake inhibitor Sertraline Sibutramine Superfamily
Functional Category Approved Drug
No. of Members 7
Class Class 48

Member Families of This Superfamily

Family NameSeedsMembers
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 10
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Putative Ring-substituted 2-amino-1 2 3 4-tetrahydronaphthalen... 1 0
Putative Sulfonamide Derivatives As 5ht7 Receptor Antagonists ... 2 0
Putative Therapeutic Agents In Patent US4746680,US6127424,US47... 1 0
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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