CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSAD528
Superfamily Name Tumor necrosis factor Inhibitor Thalidomide Superfamily
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 9
Class Class 486

Member Families of This Superfamily

Family NameSeedsMembers
Interstitial collagenase and 72 kDa type IV collagenase inhibi... 1 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Peptide deformylase inhibitor (2S)-N-benzoyl-1-[(2R)-2-(cyclop... 2 2
Prolyl endopeptidase inhibitor 2-{3-[(2s)-4,4-Difluoro-2-(Pyrr... 2 2
Putative Patent EP0483631 Family 1 0
Putative Patent US5250676,EP0564129 Family 1 0
Putative Patent WO0055134 Family 2 2 0
Putative Patent WO9609295 Family 2 1 0
Tumor necrosis factor Inhibitor Thalidomide Family 3 50

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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