CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSAD716
Superfamily Name Bacterial outer membrane Inhibitor Polymyxin B Superfamily
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 12
Class Class 607

Member Families of This Superfamily

Family NameSeedsMembers
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
N-[(4S)-2,2-dimethyloxan-4-yl]-4-methyl-3-phenylpentanamide NP... 4 0
Pepsin A and Renin inhibitor N-[(3R)-1-[[(1S)-1-hydroxy-3-[[(2... 1 0
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Pol polyprotein inhibitor Diol-Based HIV-1 protease inhibitor ... 1 0
Putative Patent EP0417143,WO8911856 Family 4 1 0
Putative Patent US5750648 Family 1 0
Renin inhibitor (2S)-2-[(2S)-1-(azetidin-1-yl)-1-oxo-3-phenylp... 1 0
Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1
Renin inhibitor [(2R)-1-[[(2S,3S,5R)-6-(butylamino)-1-cyclohex... 5 4
Stromelysin-1 and Caspase-1 inhibitor Berkeleyamide A family 1 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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