CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSAD726
Superfamily Name Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Superfamily
Functional Category Approved Drug with Natural Product
No. of Members 12
Class Class 484

Member Families of This Superfamily

Family NameSeedsMembers
6-oxo-N-quinolin-6-ylpyran-3-carboxamide NP 2-oxo-n-(quinolin-... 1 0
Aldose reductase inhibitor AGN-PC-0AKSQU family 2 0
Bile acid receptor ligand methyl (E)-3-[3-[2-methylpropanoyl-[... 2 0
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
NP 4-(2-(pyridin-3-yl)piperidin-1-yl)-1-oxaspiro[4.5]dec-3-en-... 2 0
NP Methyl 6-oxo-1-(pyridin-2-ylmethyl)-1,6-dihydropyridine-3-c... 2 0
Putative Anti-inflammatory Furanones In Patent US5134128 Family 1 0
Putative Hydrolyzable Silyl-substituted Dyestuffs For Transfer... 1 0
Putative Patent US4309537,US4312875,US4264612 Family 1 0
Putative Patent US4769380,US4312875 Family 2 0
Putative Patent US5153214,US5025025 Family 2 1 0
Thromboxane-A synthase inhibitor (Z)-2-bromo-3-[4-(pyridin-3-y... 1 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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