CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSAD74
Superfamily Name Thyroid hormone receptor alpha ligand thyroid hormone analog Liothyronine Superfamily
Functional Category Approved Drug with Human Metabolite & Natural Product
No. of Members 13
Class Class 74

Member Families of This Superfamily

Family NameSeedsMembers
3-azaniumyl-3-(4-butoxyphenyl)butanoate NP 3-amino-3-(4-butoxy... 2 0
3-azaniumyl-3-(4-methoxynaphthalen-1-yl)propanoate NP ZINC0027... 2 1
Putative NP ZINC00050501 Family 6 4
Putative Patent EP0641319,US5643878 Family 2 0
Putative Patent EP0866073,US5968581 Family 1 0
Putative Patent EP0937703 Family 1 0
Putative Patent WO0078344 Family 1 0
Putative Patent WO8600522 Family 1 0
Putative Patent WO9958510 Family 2 1 0
Putative Phenylalanine Derivatives As Endothelin Antagonists I... 1 0
Putative Renal-selective Prodrugs For The Treatment Of Hyperte... 1 0
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Tyrosine-protein phosphatase non-receptor type 1 ligand FLUORO... 1 1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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