CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSBM4495
Superfamily Name Tyrosine-protein kinase JAK2 and Aurora kinase A Binder Superfamily
Functional Category Bioactive
No. of Members 11
Class Class 712

Member Families of This Superfamily

Family NameSeedsMembers
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodi... 1 4
Putative Patent US5369104 Family 1 0
Putative Sulfonamide Derivatives In Patent WO9830564 Family 1 0
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 3 5
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 1 0
Tyrosine-protein kinase JAK2 and ALK tyrosine kinase receptor ... 5 0
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-0CSEAG family 2 1
Tyrosine-protein kinase JAK2 inhibitor N-[2-[2-[3-chloro-4-(4-... 2 0
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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