CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSBM6359
Superfamily Name Caspase-3 and Caspase-7 Binder Superfamily 4
Functional Category Bioactive with Natural Product
No. of Members 10
Class Class 2449

Member Families of This Superfamily

Family NameSeedsMembers
Caspase-3 and Caspase-7 inhibitor (2S)-N-[(3S)-2-hydroxy-5-oxo... 4 1
Coagulation factor X and Prothrombin inhibitor 3-[4-carbamimid... 3 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Integrin beta-3 and Integrin alpha-IIb inhibitor 3-[[4-(4-carb... 1 1
Leukotriene A-4 hydrolase inhibitor (2S)-2-amino-5-oxo-5-[4-(4... 1 0
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Putative Hiv Protease Inhibitors In Patent US6043357 Family 1 0
Putative Patent US4863939 Family 1 0
Putative Patent US4873253,EP0284632 Family 1 0
Putative Patent US5455348 Family 2 3 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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