CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSBM820
Superfamily Name LIM domain kinase 2 and RAC-alpha serine/threonine-protein kinase Binder Superfamily
Functional Category Bioactive
No. of Members 10
Class Class 920

Member Families of This Superfamily

Family NameSeedsMembers
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Epidermal growth factor receptor and Receptor tyrosine-protein... 1 0
LIM domain kinase 1 and LIM domain kinase 2 inhibitor (2S)-N'-... 9 0
LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... 4 0
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... 11 6
Receptor-type tyrosine-protein kinase FLT3 ligand 4-[6-amino-5... 1 1
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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