CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSBM894
Superfamily Name Proteinase-activated receptor 1 and Vascular endothelial growth factor receptor 2 Binder Superfamily
Functional Category Bioactive
No. of Members 8
Class Class 2321

Member Families of This Superfamily

Family NameSeedsMembers
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Proteinase-activated receptor 1 ligand (3R,3aS,4S,4aR,8aS,9aR)... 1 11
Proteinase-activated receptor 1 ligand 2-[(E)-2-[(1R,3R,3aS,4S... 1 0
Proteinase-activated receptor 1 ligand 2-[2-[(E)-2-[(3R,3aS,4S... 1 2
Putative Patent EP0153006,US4530929 Family 1 0
Putative Substituted Indolinone As Tyrosine Kinase Inhibitors ... 2 0
Putative Substituted Tricyclics In Patent WO9818464 Family 1 0
Vascular endothelial growth factor receptor 2 ligand indolyl q... 2 1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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