CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD128
Superfamily Name Cyclin-dependent kinase 2 Inhibitor Seliciclib Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 12
Class Class 920

Member Families of This Superfamily

Family NameSeedsMembers
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Dual specificity protein kinase TTK inhibitor 4-[[2-(2-methyl-... 1 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Putative Patent EP0362645 Family 2 0
Putative Patent US5618814 Family 3 1 0
Serine/threonine-protein kinase B-raf inhibitor imidazole-base... 2 0
Serine/threonine-protein kinase mTOR Inhibitor (4-(6-morpholin... 2 11
Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... 2 15
Transient receptor potential cation channel subfamily V member... 4 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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