CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD151
Superfamily Name Mitogen-activated protein kinase 12 Inhibitor VX-702 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 8
Class Class 824

Member Families of This Superfamily

Family NameSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Dipeptidyl peptidase 4 inhibitor 6-(aminomethyl)-5-(2-bromo-5-... 6 1
Dipeptidyl peptidase 4 inhibitor 7-amino-6-(aminomethyl)-5-(2-... 1 6
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 1 0
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Putative 7-cycloalkyl Naphthyridines In Patent EP0677052,WO941... 2 0
Putative Novel 7-substituted Quinazolin-2 4-diones Useful As A... 1 0
Putative Patent US4282223 Family 1 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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