CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD214
Superfamily Name Insulin-like growth factor 1 receptor Ligand AEW-541 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 17
Class Class 976

Member Families of This Superfamily


Family NameSeedsMembers
Activated CDC42 kinase 1 inhibitor 5-(2-fluorophenyl)-N-[[(2S)... 5 0
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Melatonin receptor type 1A ligand N-[2-(5-methoxy-2-phenyl-1H-... 1 2
Neuropeptide Y receptor type 5 ligand 3-[2-[6-[2-[(2-methylpro... 1 0
Neuropeptide Y receptor type 5 ligand 7-methoxy-2-methyl-6-phe... 1 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Serine/threonine-protein kinase B-raf and RAF proto-oncogene s... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 1 0
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 1 0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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