CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD22
Superfamily Name Gastrin-releasing peptide receptor and Arachidonate 5-lipoxygenase-activating protein Binder Superfamily
Functional Category Clinical Trial Drug
No. of Members 10
Class Class 831

Member Families of This Superfamily

Family NameSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor AM803... 1 0
Beta-secretase 1 and Beta-secretase 2 inhibitor 7-fluoro-3-(5-... 2 7
Cathepsin S and Cathepsin K inhibitor 2-cyano-pyrropyrimidine,... 4 1
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Gastrin-releasing peptide receptor Ligand GSK1292263 Family 1 0
Glucose-dependent insulinotropic receptor ligand (2R)-2-[1-(5-... 4 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Orexin receptor type 1 and Orexin receptor type 2 ligand (1R,2... 6 1
Putative Patent US5010200,US4962109 Family 2 1 0
Putative Patent US5626791 Family 2 4 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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