CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD247
Superfamily Name Calcium-activated potassium channel subunit alpha-1 Ligand AVE0118 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 17
Class Class 656

Member Families of This Superfamily

Family NameSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(quinoline-5-carb... 1 0
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 5
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 4 0
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Mitogen-activated protein kinase 14 inhibitor 3-fluoro-N-[4-me... 2 5
Prothrombin and Coagulation factor X inhibitor N-[3-[(3-fluoro... 1 8
Putative Patent US4791129,US4725616 Family 1 0
Putative Patent US5936098 Family 1 0
Serine/threonine-protein kinase Chk1 inhibitor 9-(1-methylpyrr... 1 1
Serine/threonine-protein kinase Chk1 inhibitor Chk1_97 family 1 1
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... 2 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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