CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD482
Superfamily Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform and Serine/threonine-protein kinase mTOR Inhibitor BEZ235 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 13
Class Class 147

Member Families of This Superfamily


Family NameSeedsMembers
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
Acyl-CoA:cholesterol acyltransferase inhibitor AGN-PC-00GCQW f... 2 1
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9057529 f... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 5 0
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
Macrophage colony-stimulating factor 1 receptor and Vascular e... 2 3
Neuropeptide Y receptor type 5 ligand AGN-PC-07CNLC family 1 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 9
Putative New Pharmaceutically Active Compounds In Patent WO007... 2 0
Putative Patent US4851406,EP0223937 Family 2 1 0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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