CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD587
Superfamily Name Smoothened homolog Inhibitor LDE225 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 8
Class Class 1163

Member Families of This Superfamily


Family NameSeedsMembers
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Neutrophil elastase inhibitor AGN-PC-07C6MH family 3 0
Putative Nicotinic Acid Esters In Patent US5658910 Family 1 0
Retinoic acid receptor RXR-alpha ligand 6-[N-ethyl-5-(2-methyl... 1 13
Reverse transcriptase/RNaseH and Cytochrome P450 2C19 inhibito... 7 2
Reverse transcriptase/RNaseH inhibitor Dipyridodiazepinone der... 1 8
Smoothened homolog Inhibitor LDE225 Family 3 76
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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