CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD630
Superfamily Name Angiopoietin-1 receptor and Vascular endothelial growth factor receptor 1 Binder Superfamily
Functional Category Clinical Trial Drug
No. of Members 18
Class Class 195

Member Families of This Superfamily


Family NameSeedsMembers
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Alpha-1B adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 4
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
PHA848125 family 13 138
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Proto-oncogene tyrosine-protein kinase receptor Ret ligand (2E... 1 0
Putative Substituted 1 7-annelated 1h-indazoles In Patent US49... 1 0
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 12 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27270 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543