CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD64
Superfamily Name Gamma-secretase subunit APH-1B Inhibitor E2012 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 10
Class Class 869

Member Families of This Superfamily

Family NameSeedsMembers
Aromatase Inhibitor 3-(imidazolylmethyl)-4'-nitroflavone Family 4 1
Aromatase Inhibitor 4-imidazol-1-ylmethyl-1-nitro-xanthen-9-on... 3 1
Cellular tumor antigen p53 and E3 ubiquitin-protein ligase Mdm... 2 0
Cytochrome P450 11B1, mitochondrial and Aromatase inhibitor CH... 2 1
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
NP N-(1-((3-(1h-imidazol-1-yl)propyl)amino)-3-methyl-1-oxobuta... 2 0
Putative Carbostyril Derivatives In Patent WO9426732,US5541198... 2 0
Putative Inhibitors Of Farnesyl-protein Transferase In Patent ... 1 0
Putative Patent US4680293 Family 1 0
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 4

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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