CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD727
Superfamily Name Dual specificity mitogen-activated protein kinase kinase Inhibitor Mek-inhibitor Superfamily
Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
No. of Members 9
Class Class 1330

Member Families of This Superfamily

Family NameSeedsMembers
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 9h-bet... 1 1
Putative Black-pigmented Structured High Molecular Weight Mate... 1 0
Putative Compounds Serine Protease Inhibitors In Patent WO0077... 1 0
Putative Hexahydro-diazepino-indole Derivatives In Patent US39... 2 0
Putative Indolin-2-one Derivatives In Patent US6114536,US60311... 1 0
Putative Indolinone Compounds As Kinase Inhibitors In Patent W... 1 0
Putative Patent US5965579,EP0311135,US5723483 Family 2 0
Putative Patent US6147106 Family 2 1 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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