CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSCD754
Superfamily Name Vascular endothelial growth factor receptor 2 Ligand XL999 Superfamily
Functional Category Clinical Trial Drug with Natural Product
No. of Members 13
Class Class 1053

Member Families of This Superfamily

Family NameSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Glycogen synthase kinase-3 beta inhibitor 3-(5-bromo-1-methyli... 1 0
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA4D family 1 0
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... 1 0
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 8
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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