CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID1083
Superfamily Name Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-imidazol-1-yl-phenoxy)-propyl]-pyridine Superfamily
Functional Category Investigative Drug with Natural Product
No. of Members 16
Class Class 976

Member Families of This Superfamily


Family NameSeedsMembers
Acyl-CoA:cholesterol acyltransferase inhibitor AGN-PC-073SIX f... 1 1
Adenosine receptor A2a ligand N-(5-cyano-3-phenylimidazol-4-yl... 2 0
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
D(2) dopamine receptor ligand SureCN11039666 family 1 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
Histone deacetylase 1 and Histone deacetylase 8 inhibitor (E)-... 1 0
Melanin-concentrating hormone receptor 1 ligand SureCN3334861 ... 1 3
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Melatonin receptor type 1B ligand CHEMBL1802020 family 2 7
Metabotropic glutamate receptor 2 ligand 2-[[(1R,5S)-6-[(2,5-d... 2 3
Nociceptin receptor and Delta-type opioid receptor ligand 2-[3... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 15
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 1
Putative Substituted Benzimidazole Derivatives Possessing Clas... 1 0
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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