CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID1202
Superfamily Name Caspase-3 and Histamine H3 receptor Binder Superfamily
Functional Category Investigative Drug with Natural Product
No. of Members 10
Class Class 893

Member Families of This Superfamily

Family NameSeedsMembers
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-[(3,4... 1 6
Cytochrome P450 1A2 and Cytochrome P450 3A4 inhibitor 4-[4-[2-... 2 3
Histamine H3 receptor ligand 4-[[2-[2-[(2R)-2-methylpyrrolidin... 1 1
Histamine H3 receptor Ligand A-349821 Family 49 228
Putative 2-substituted Phenyl-5-triazols {8 5 1-a{9 {0 Isoquin... 2 0
Putative Isoquinolyl Substituted Hydroxylamine Derivatives In ... 1 0
Rho-associated protein kinase 1 and Rho-associated protein kin... 1 7
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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