CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID1271
Superfamily Name Mitogen-activated protein kinase 14 and Serine/threonine-protein kinase B-raf Inhibitor ZM-336372 Superfamily
Functional Category Investigative Drug with Natural Product
No. of Members 8
Class Class 418

Member Families of This Superfamily

Family NameSeedsMembers
1-hydroxy-N-(2-hydroxyphenyl)-3-oxo-3,5,6,7-tetrahydropyrido[3... 1 0
Cyclin-dependent kinase 4 inhibitor SureCN13343915 family 2 2
Kinesin-like protein KIF11 inhibitor 2-benzyl-3-(4-hydroxyphen... 2 5
Kinesin-like protein KIF11 inhibitor 3-benzyl-2-(3-hydroxyphen... 2 1
Metabotropic glutamate receptor 5 ligand CPPHA family 1 0
Mitogen-activated protein kinase 14 and Serine/threonine-prote... 1 1
Serine/threonine-protein kinase B-raf inhibitor 5,6-bis(3-hydr... 2 2
Vascular endothelial growth factor receptor 2 ligand CHEMBL197... 1 1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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