CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID174
Superfamily Name Estradiol 17-beta-dehydrogenase 1 and Inosine-5'-monophosphate dehydrogenase 2 Binder Superfamily
Functional Category Investigative Drug
No. of Members 4
Class Class 1256

Member Families of This Superfamily

Family NameSeedsMembers
Estradiol 17-beta-dehydrogenase 1 Inhibitor EM-1745 Family 2 10
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor C2-MAD Family 3 24
Putative Patent EP0983291,WO9811123,US6166188 Family 3 0
Putative Patent US5955600,US6103891 Family 1 0

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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