CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID494
Superfamily Name Histamine H3 receptor and Alpha-2A adrenergic receptor Binder Superfamily
Functional Category Investigative Drug with Human Metabolite & Natural Product
No. of Members 13
Class Class 1671

Member Families of This Superfamily

Family NameSeedsMembers
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Benzodioxoles Metabolite Oxmetidine Family 1 2
Histamine H3 receptor Ligand Verongamine Family 1 0
Histidinol dehydrogenase inhibitor (3S)-3-amino-1-(1,3-benzodi... 1 0
NP N-(2-(1h-imidazol-4-yl)ethyl)-2-((2-oxo-3-phenyl-2h-chromen... 3 0
NP N-(2-(1h-imidazol-4-yl)ethyl)-2-(7-hydroxy-4-methyl-2-oxo-2... 16 0
propanoate NP ZINC40309138 Family 20 1
Prothrombin inhibitor AGN-PC-09QMX4 family 1 4
Putative Ketone Derivatives In Patent US5019586,US4918080,EP02... 1 0
Putative NP ZINC20112670 Family 20 1
Putative NP ZINC32497112 Family 6 0
Putative NP ZINC40310111 Family 26 0
Putative NP ZINC40310254 Family 74 1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



83107 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543