CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID605
Superfamily Name Cathepsin K and Cathepsin S Binder Superfamily
Functional Category Investigative Drug
No. of Members 9
Class Class 1127

Member Families of This Superfamily

Family NameSeedsMembers
Cathepsin K and Cathepsin S Inhibitor P2,p3 Ketoamide Derivati... 2 1
FK506-binding protein 1A Inhibitor Gpi-1046 Family 4 10
G-protein coupled bile acid receptor 1 ligand methyl 2-[3,5-bi... 1 0
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 2 1
Putative Heterocyclic Amide Compounds As Cell Adhesion Inhibit... 1 0
Putative Multicyclic Compounds Which Inhibit Leukocyte Adhesio... 1 0
Putative Substituted 4-(1h-benzimidazol-2-yl) 1 4]diazepanes U... 1 0
Receptor-type tyrosine-protein phosphatase beta ligand AGN-PC-... 1 2
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S,4R)... 2 2

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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