CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Superfamily Information

CFAM Superfamily ID CFSID676
Superfamily Name Macrophage metalloelastase Inhibitor PF-00356231 Superfamily
Functional Category Investigative Drug with Natural Product
No. of Members 15
Class Class 1827

Member Families of This Superfamily


Family NameSeedsMembers
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(3-fluorophen... 1 6
Cannabinoid receptor 1 ligand N-(cyclobutylmethyl)-3-[[4-(meth... 1 1
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Mineralocorticoid receptor ligand 1-(2-hydroxyethyl)-4-methyl-... 1 0
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-073U... 3 8
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
Orexin receptor type 2 and Orexin receptor type 1 ligand 2-(1-... 3 0
Platelet-activating factor receptor ligand (4R)-N-(3-benzoylph... 2 1
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 1 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 1 1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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