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PROFEAT - Protein Feature Server (2016)                                                                                        Return to HOME

PROFEAT is a web server for computing commonly used proteins features from amino acid sequence, and interaction network properties from network structure.

🔑 Reference Manual and User Guide
🔑 Network Descriptor Tutorial NEW!
🔑 Structure Descriptor Tutorial NEW!

Biological Network Descriptors

Un-Directed Network:

 Un-Weighted Network   upload your network,   or upload sample networknetwork_sample_unweighted.png

Please upload the network file in SIF format or NET format:

Upload Network File


Sample Un-Weighted Network File HERE

 Edge-Weighted Networkupload your network,   or upload sample networknetwork_sample_edge_weighted.png

Please upload the network file in Edge-Weighted SIF format or Edge-Weighted NET format:

Upload Network File


Sample Edge-Weighted Network File HERE

 Node-Weighted Networkupload your network,   or upload sample networknetwork_sample_node_weighted.png

Please upload the network file in SIF format or NET format:

Upload Network File


Please upload the node weight file in Node-Weighted TXT format:

Upload Node Weight File


Sample Network File HERE

Sample Node Weight File HERE

 Edge & Node-Weighted Networkupload your network,   or upload sample networknetwork_sample_edge_node_weighted.png

Please upload the network file in Edge-Weighted SIF format or Edge-Weighted NET format:

Upload Network File


Please upload the node weight file in Node-Weighted TXT format:

Upload Node Weight File


Sample Edge-Weighted Network File HERE

Sample Node Weight File HERE

Directed Network:

 Un-Weighted Network   upload your network,   or upload sample networknetwork_sample_directed.png

Please upload the network file in Directed SIF format or Directed NET format:

Upload Network File


Sample Directed Un-Weighted Network File HERE

FullSlim    

How to cite our database

P. Zhang, L. Tao, X. Zeng, C. Qin, S.Y. Chen, F. Zhu, Z.R. Li, Y.Y. Jiang, W.P. Chen, Y.Z. Chen. A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks. Brief Bioinform. pii: bbw071 (2016).

P. Zhang, L. Tao, X. Zeng, C. Qin, S.Y. Chen, F. Zhu, S.Y. Yang, Z.R. Li, W.P. Chen, Y.Z. Chen. PROFEAT Update: A Protein Features Web Server with Added Facility to Compute Network Descriptors for Studying Omics-Derived Networks. J Mol Biol. pii:S0022-2836(16)30428-4. (2016).

H.B. Rao, F. Zhu, G.B. Yang, Z.R. Li, and Y.Z. Chen. Update of PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence. Nucleic Acids Res. Jul 1, 2011; 39(Web Server issue):W385-90.

Z.R. Li, H.H. Lin, L.Y. Han, L. Jiang, X. Chen, and Y.Z. Chen. PROFEAT: A Web Server for Computing Structural and Physicochemical Features of Proteins and Peptides from Amino Acid Sequence. Nucleic Acids Res. Jul 1, 2006; 34(Web Server issue):W32-7.

List of Publications That Used the Features in PROFEAT

The earlier version of PROFEAT can be found HERE.

Last updated: 30 May 2016

visits since November 6, 2005


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If you find any error in data or bug in web service, please kindly report it to Dr. Tao Lin or Mr. Zhang Peng.



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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